SUPERVISED MACHINE LEARNING CLASSIFICATION OF PSYCHOSIS BIOTYPES BASED ON BRAIN STRUCTURE: FINDINGS FROM THE BIPOLAR-SCHIZOPHRENIA NETWORK FOR INTERMEDIATE PHENOTYPES (B-SNIP)

Abstract Traditional diagnostic formulations of psychotic disorders have low correspondence with underlying disease neurobiology.This has led to a growing interest in using brain-based biomarkers to capture Conditioner biologically-informed psychosis constructs.Building upon our prior work on the B-SNIP Psychosis Biotypes, we aimed to examine wheth

The Bacillus subtilis GlmR (formerly YvcK) protein is essential for growth on gluconeogenic carbon sources.Mutants lacking GlmR display a variety of phenotypes suggestive of impaired cell wall synthesis including antibiotic sensitivity, aberrant cell morphology and lysis.To define the role of GlmR, we selected suppressor mutations that ameliorate t

Retinopathy of prematurity (ROP) is caused Furniture by abnormal retinal vascularization in premature infants that has the potential for severe long-term vision impairment.Recent advancements in handheld optical coherence tomography (OCT) have enabled noninvasive, high-resolution, cross-sectional imaging of the infant eye at the bedside.The use of

Abstract Background Tembusu virus (TMUV) usually affects adult ducks, causing a severe drop of egg production.It has also been shown to be pathogenic in commercial Pekin ducklings below 7 Used Cage weeks of age.Here, we report a TMUV-caused neurological disease in young egg-type ducklings and the pathogenicity of the egg-type duck-origin TMUV isola

The cladoceran Daphnia lumholtzi is a subtropical and tropical zooplankter, and an invasive species in North America.Thus far, D.lumholtzi has not been detected in Europe.Here we investigated whether a hypothetical introduction to Europe could result in a successful invasion, either now or in the near future when facilitated by climate change.In la